› 3a2p

X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed: 
1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-146563 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6-aminohexanoate-cyclic-dimer hydrolase Chain: A
Molecule details ›
Chain: A
Length: 493 amino acids
Theoretical weight: 52.26 KDa
Source organism: Paenarthrobacter ureafaciens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13398 (Residues: 1-493; Coverage: 100%)
Gene name: nylA
Sequence domains: Amidase
Structure domains: Amidase signature (AS) domain

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P62
Unit cell:
a: 130.75Å b: 130.75Å c: 58.23Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.181 0.214
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Scope, limitations and classification of lactamases.
Assaf et al. (2016)
1 more

3 mentions without citation

BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin.
Wang et al. (2018)
2 more