› 3aai

X-ray diffraction
2.1Å resolution

X-ray crystal structure of CsoR from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb3aai/pdb
PDB entry 3aai coloured by chain, front view.
PDB entry 3aai coloured by chain, side view.
PDB entry 3aai coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Primary publication:
Structural and functional characterization of the transcriptional repressor CsoR from Thermus thermophilus HB8.
Sakamoto K, Agari Y, Agari K, Kuramitsu S, Shinkai A
Microbiology (Reading) 156 1993-2005 (2010)
PMID: 20395270

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177880 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Copper-sensing transcriptional repressor CsoR Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 94 amino acids
Theoretical weight: 11.07 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SHL1 (Residues: 1-94; Coverage: 100%)
Gene name: TTHA1719
Sequence domains: Metal-sensitive transcriptional repressor
Structure domains: Metal-sensitive repressor, helix protomer

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P32
Unit cell:
a: 63.198Å b: 63.198Å c: 81.033Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.244 0.288
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Copper-responsive gene regulation in bacteria.
Rademacher et al. (2012)
2 more

1 mention without citation

Glutamate Ligation in the Ni(II)- and Co(II)-Responsive Escherichia coli Transcriptional Regulator, RcnR.
Carr et al. (2017)