› 3aco

X-ray diffraction
2.7Å resolution

Crystal structure of the EFC/F-BAR domain of human PACSIN2/Syndapin II (2.7 A)

Released:
DOI: 10.2210/pdb3aco/pdb
PDB entry 3aco coloured by chain, front view.
PDB entry 3aco coloured by chain, side view.
PDB entry 3aco coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II.
Shimada A, Takano K, Shirouzu M, Hanawa-Suetsugu K, Terada T, Toyooka K, Umehara T, Yamamoto M, Yokoyama S, Suetsugu S
FEBS Lett 584 1111-8 (2010)
PMID: 20188097

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193992 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C and casein kinase substrate in neurons protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 350 amino acids
Theoretical weight: 41.03 KDa
Source organism: Homo sapiens
Expression system: cell free system (Escherichia coli)
UniProt:
  • Canonical: Q9UNF0 (Residues: 1-343; Coverage: 71%)
Gene name: PACSIN2
Sequence domains: Fes/CIP4, and EFC/F-BAR homology domain
Structure domains: Arfaptin homology (AH) domain/BAR domain

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
1 modified residue:
Ligand MSE 22 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P212121
Unit cell:
a: 31.607Å b: 84.654Å c: 357.335Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.226 0.279
Expression system: cell free system (Escherichia coli)

Quick links

Citations

12 review citations

Let's go bananas: revisiting the endocytic BAR code.
Qualmann et al. (2011)
11 more