3anz

X-ray diffraction
2.3Å resolution

Crystal Structure of alpha-hemolysin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
PDBe Complex ID:
PDB-CPX-101947 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukocidin/Hemolysin toxin domain-containing protein Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b
Length: 302 amino acids
Theoretical weight: 34.51 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3JRX7 (Residues: 27-319; Coverage: 100%)
Gene name: SAV1163
Sequence domains: Leukocidin/Hemolysin toxin family
Structure domains: Leukocidin/porin MspA

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P21
Unit cell:
a: 102.821Å b: 293.877Å c: 170.545Å
α: 90° β: 92.42° γ: 90°
R-values:
R R work R free
0.204 0.193 0.226
Expression system: Escherichia coli