3b2d

X-ray diffraction
2.8Å resolution

Crystal structure of human RP105/MD-1 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-131989 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
CD180 antigen Chains: A, B
Molecule details ›
Chains: A, B
Length: 603 amino acids
Theoretical weight: 67.51 KDa
Source organism: Homo sapiens
Expression system: Drosophila
UniProt:
  • Canonical: Q99467 (Residues: 24-626; Coverage: 95%)
Gene names: CD180, LY64, RP105
Sequence domains:
Lymphocyte antigen 86 Chains: C, D
Molecule details ›
Chains: C, D
Length: 144 amino acids
Theoretical weight: 15.99 KDa
Source organism: Homo sapiens
Expression system: Drosophila
UniProt:
  • Canonical: O95711 (Residues: 21-162; Coverage: 100%)
Gene names: LY86, MD1
Sequence domains: ML domain
Structure domains: Immunoglobulin-like

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P21212
Unit cell:
a: 203.997Å b: 66.441Å c: 119.097Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.218 0.284
Expression system: Drosophila