Function and Biology Details
Reactions catalysed:
Xanthine + NAD(+) + H(2)O = urate + NADH
Xanthine + H(2)O + O(2) = urate + H(2)O(2)
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
- Aldehyde oxidase/xanthine dehydrogenase-like
- CO dehydrogenase flavoprotein, C-terminal
- 2Fe-2S ferredoxin-type iron-sulfur binding domain
- Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain
- Oxidoreductase, molybdopterin binding site
- Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain
- Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily
- Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
12 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Xanthine dehydrogenase/oxidase (preferred)
PDBe Complex ID:
PDB-CPX-160412 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Xanthine dehydrogenase/oxidase
Molecule details ›
Chains: A, I
Length: 219 amino acids
Theoretical weight: 24.04 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Structure domains:
Length: 219 amino acids
Theoretical weight: 24.04 KDa
Source organism: Bos taurus
UniProt:
- Canonical:
P80457 (Residues: 1-219; Coverage: 16%)
Sequence domains:
Structure domains:
Xanthine dehydrogenase/oxidase
Molecule details ›
Chains: B, J
Length: 350 amino acids
Theoretical weight: 39.01 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Structure domains:
Length: 350 amino acids
Theoretical weight: 39.01 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P80457 (Residues: 220-569; Coverage: 26%)
Sequence domains:
Structure domains:
Xanthine dehydrogenase/oxidase
Molecule details ›
Chains: C, K
Length: 763 amino acids
Theoretical weight: 83.96 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 763 amino acids
Theoretical weight: 83.96 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P80457 (Residues: 570-1332; Coverage: 57%)
Sequence domains:
- Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
- Molybdopterin cofactor-binding domain
- Molybdopterin cofactor-binding domain
