› 3bb7

X-ray diffraction
1.5Å resolution

Structure of Prevotella intermedia prointerpain A fragment 39-359 (mutant C154A)

Released:
DOI: 10.2210/pdb3bb7/pdb
PDB entry 3bb7 coloured by chain, front view.
PDB entry 3bb7 coloured by chain, side view.
PDB entry 3bb7 coloured by chain, top view.
Source organism: Prevotella intermedia
Primary publication:
A new autocatalytic activation mechanism for cysteine proteases revealed by Prevotella intermedia interpain A.
Mallorquí-Fernández N, Manandhar SP, Mallorquí-Fernández G, Usón I, Wawrzonek K, Kantyka T, Solà M, Thøgersen IB, Enghild JJ, Potempa J, Gomis-Rüth FX
J Biol Chem 283 2871-82 (2008)
PMID: 17993455

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interpain A Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 35.06 KDa
Source organism: Prevotella intermedia
Expression system: Escherichia coli
UniProt:
  • Canonical: A9J7N5 (Residues: 84-403; Coverage: 37%)
Gene name: pin0048
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 128.87Å b: 38.81Å c: 78.14Å
α: 90° β: 127.26° γ: 90°
R-values:
R R work R free
0.156 0.155 0.193
Expression system: Escherichia coli

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Citations

1 review citation

Complement evasion strategies of pathogens-acquisition of inhibitors and beyond.
Blom et al. (2009)
29 other articles

2 mentions without citation

Progress in super long loop prediction.
Zhao et al. (2011)
1 more