› 3bno

X-ray diffraction
2.35Å resolution

Crystal Structure of the Homo sapiens Mitochondrial Ribosomal Decoding Site (Br-derivative)

Released:
DOI: 10.2210/pdb3bno/pdb
PDB entry 3bno coloured by chain, front view.
PDB entry 3bno coloured by chain, side view.
PDB entry 3bno coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
The bacterial and mitochondrial ribosomal A-site molecular switches possess different conformational substates.
Kondo J, Westhof E
Nucleic Acids Res 36 2654-66 (2008)
PMID: 18346970

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196636 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
A site of human mitochondrial ribosome Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 21 nucleotides
Theoretical weight: 6.77 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 5BU 4 x 5BU

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P1
Unit cell:
a: 35.14Å b: 45.46Å c: 52.13Å
α: 71.43° β: 73.42° γ: 74.05°
R-values:
R R work R free
0.226 0.226 0.255
Expression system: Not provided

Quick links

Citations

6 review citations

The future of aminoglycosides: the end or renaissance?
Houghton et al. (2010)
5 more

1 mention without citation

The bacterial and mitochondrial ribosomal A-site molecular switches possess different conformational substates.
Kondo et al. (2008)