› 3bnp

X-ray diffraction
2.7Å resolution

Crystal Structure of the Homo sapiens Mitochondrial Ribosomal Decoding Site (A1555G Mutant)

Released:
DOI: 10.2210/pdb3bnp/pdb
PDB entry 3bnp coloured by chain, front view.
PDB entry 3bnp coloured by chain, side view.
PDB entry 3bnp coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
The bacterial and mitochondrial ribosomal A-site molecular switches possess different conformational substates.
Kondo J, Westhof E
Nucleic Acids Res 36 2654-66 (2008)
PMID: 18346970

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196637 (preferred)
Entry contents:
2 distinct RNA molecules
Macromolecules (2 distinct):
A site of human mitochondrial ribosome, A chain Chain: A
Molecule details ›
Chain: A
Length: 22 nucleotides
Theoretical weight: 7.02 KDa
Source organism: Synthetic construct
Expression system: Not provided
A site of human mitochondrial ribosome, B chain Chain: B
Molecule details ›
Chain: B
Length: 21 nucleotides
Theoretical weight: 6.72 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand K 1 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3121
Unit cell:
a: 66.35Å b: 66.35Å c: 57.35Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.231 0.27
Expression system: Not provided

Quick links

Citations

5 review citations

The future of aminoglycosides: the end or renaissance?
Houghton et al. (2010)
4 more

5 mentions without citation

RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.
Šponer et al. (2018)
4 more