› 3boc

X-ray diffraction
1.8Å resolution

Carbonic anhydrase from marine diatom Thalassiosira weissflogii- zinc bound domain 2 (CDCA1-R2)

Released:
DOI: 10.2210/pdb3boc/pdb
PDB entry 3boc coloured by chain, front view.
PDB entry 3boc coloured by chain, side view.
PDB entry 3boc coloured by chain, top view.
Source organism: Conticribra weissflogii
Primary publication:
Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Xu Y, Feng L, Jeffrey PD, Shi Y, Morel FM
Nature 452 56-61 (2008)
PMID: 18322527

Function and Biology Details

Reaction catalysed: 
H(2)CO(3) = CO(2) + H(2)O
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175898 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadmium-specific carbonic anhydrase Chain: A
Molecule details ›
Chain: A
Length: 210 amino acids
Theoretical weight: 22.43 KDa
Source organism: Conticribra weissflogii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q50EL4 (Residues: 197-406; Coverage: 34%)
Gene name: cdca1
Sequence domains: Cadmium carbonic anhydrase repeat

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21212
Unit cell:
a: 64.814Å b: 77.909Å c: 37.705Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.21 0.261
Expression system: Escherichia coli

Quick links

Citations

48 review citations

Metalloproteins and metal sensing.
Waldron et al. (2009)
47 more

1 mention without citation

Mitochondrial biology. Replication-transcription switch in human mitochondria.
Agaronyan et al. (2015)