› 3bpj

X-ray diffraction
1.85Å resolution

Crystal structure of human translation initiation factor 3, subunit 1 alpha

Released:
DOI: 10.2210/pdb3bpj/pdb
PDB entry 3bpj coloured by chain, front view.
PDB entry 3bpj coloured by chain, side view.
PDB entry 3bpj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tempel W, Nedyalkova L, Hong B, MacKenzie F, Arrowsmith CH, Edwards AM, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131137 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 3 subunit J Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 80 amino acids
Theoretical weight: 9.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75822 (Residues: 141-220; Coverage: 31%)
Gene names: EIF3J, EIF3S1, PRO0391
Sequence domains: Translation initiation factor eIF3 subunit
Structure domains: Eukaryotic translation initiation factor 3 like domains

Ligands and Environments

1 bound ligand:
Ligand UNX 4 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P212121
Unit cell:
a: 60.902Å b: 62.373Å c: 88.056Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.229 0.263
Expression system: Escherichia coli

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