› 3bue

X-ray diffraction
2.15Å resolution

Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb3bue/pdb
PDB entry 3bue coloured by chain, front view.
PDB entry 3bue coloured by chain, side view.
PDB entry 3bue coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis.
Cherney LT, Cherney MM, Garen CR, Lu GJ, James MN
Acta Crystallogr D Biol Crystallogr 64 950-6 (2008)
PMID: 18703843

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo hexamer
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162029 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arginine repressor Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 79 amino acids
Theoretical weight: 8.14 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WPY9 (Residues: 92-170; Coverage: 47%)
Gene names: MTCY06H11.22, Rv1657, ahrC, argR
Sequence domains: Arginine repressor, C-terminal domain
Structure domains: Gyrase A; domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P1
Unit cell:
a: 53.219Å b: 57.242Å c: 57.328Å
α: 66.19° β: 62.21° γ: 82°
R-values:
R R work R free
0.171 0.168 0.235
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.
Cherney et al. (2009)
2 more

2 mentions without citation

Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis.
Cherney et al. (2008)
1 more