› 3bwq

X-ray diffraction
2.3Å resolution

Structure of free SV40 VP1 pentamer

Released:
DOI: 10.2210/pdb3bwq/pdb
PDB entry 3bwq coloured by chain, front view.
PDB entry 3bwq coloured by chain, side view.
PDB entry 3bwq coloured by chain, top view.
Source organism: Macaca mulatta polyomavirus 1
Primary publication:
Structural basis of GM1 ganglioside recognition by simian virus 40.
Neu U, Woellner K, Gauglitz G, Stehle T
Proc Natl Acad Sci U S A 105 5219-24 (2008)
PMID: 18353982

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136555 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major capsid protein VP1 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 272 amino acids
Theoretical weight: 29.73 KDa
Source organism: Macaca mulatta polyomavirus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P03087 (Residues: 31-298; Coverage: 74%)
Sequence domains: Polyomavirus coat protein
Structure domains: Capsid protein VP1,Polyomavirus

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 154.04Å b: 93.66Å c: 120.81Å
α: 90° β: 105.54° γ: 90°
R-values:
R R work R free
0.212 0.207 0.254
Expression system: Escherichia coli

Quick links

Citations

50 review citations

Mechanisms of endocytosis.
Doherty et al. (2009)
49 more

9 mentions without citation

Single-particle reconstruction statistics: a diagnostic tool in solving biomolecular structures by cryo-EM.
Heymann JB. (2019)
8 more