Function and Biology Details
Reactions catalysed:
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Glycoprotein E, immunoglobulin-like domain, flavivirus
- Envelope glycoprotein M, flavivirus
- Envelope glycoprotein M superfamily, flavivirus
- Flavivirus polyprotein propeptide
- Flavivirus polyprotein propeptide superfamily
- Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamily
- Immunoglobulin E-set
- Flaviviral glycoprotein E, central domain, subdomain 1
4 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
prM and Envelope protein E (preferred)
PDBe Complex ID:
PDB-CPX-126735 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Envelope protein E
Molecule details ›
Chain: A
Length: 402 amino acids
Theoretical weight: 44.8 KDa
Source organism: Dengue virus 2 Thailand/16681/84
Expression system: Drosophila
UniProt:
Length: 402 amino acids
Theoretical weight: 44.8 KDa
Source organism: Dengue virus 2 Thailand/16681/84
Expression system: Drosophila
UniProt:
- Canonical:
O11875 (Residues: 281-674; Coverage: 12%)
- Flavivirus glycoprotein, central and dimerisation domains
- Flavivirus glycoprotein, immunoglobulin-like domain
prM
Molecule details ›
Chain: C
Length: 130 amino acids
Theoretical weight: 14.87 KDa
Source organism: dengue virus type 2
Expression system: Drosophila
UniProt:
Structure domains: Flavivirus polyprotein propeptide domain
Length: 130 amino acids
Theoretical weight: 14.87 KDa
Source organism: dengue virus type 2
Expression system: Drosophila
UniProt:
- Canonical: Q3BCY3 (Residues: 1-130; Coverage: 20%)
Structure domains: Flavivirus polyprotein propeptide domain
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 23-ID-D
Spacegroup:
P21212
Expression system: Drosophila
