3c6o

X-ray diffraction
2.7Å resolution

Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-174445 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SKP1-like protein 1A Chain: A
Molecule details ›
Chain: A
Length: 160 amino acids
Theoretical weight: 17.88 KDa
Source organism: Arabidopsis thaliana
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q39255 (Residues: 1-160; Coverage: 100%)
Gene names: ASK1, At1g75950, SKP1, SKP1A, T4O12.17, UIP1
Sequence domains:
Structure domains: Potassium Channel Kv1.1; Chain A
Protein TRANSPORT INHIBITOR RESPONSE 1 Chain: B
Molecule details ›
Chain: B
Length: 594 amino acids
Theoretical weight: 66.88 KDa
Source organism: Arabidopsis thaliana
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q570C0 (Residues: 1-594; Coverage: 100%)
Gene names: At3g62980, FBL1, T20O10.80, TIR1, WEI1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21
Unit cell:
a: 102.264Å b: 80.836Å c: 124.748Å
α: 90° β: 104.87° γ: 90°
R-values:
R R work R free
0.187 0.183 0.272
Expression system: Spodoptera frugiperda