› 3c6v

X-ray diffraction
1.9Å resolution

Crystal structure of AU4130/APC7354, a probable enzyme from the thermophilic fungus Aspergillus fumigatus

Released:
DOI: 10.2210/pdb3c6v/pdb
PDB entry 3c6v coloured by chain, front view.
PDB entry 3c6v coloured by chain, side view.
PDB entry 3c6v coloured by chain, top view.
Source organism: Aspergillus fumigatus Af293
Entry authors: Singer AU, Binkowski TA, Skarina T, Kagan O, Edwards AM, Joachimiak A, Savchenko A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175817 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tautomerase cis-CaaD-like domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 161 amino acids
Theoretical weight: 18.75 KDa
Source organism: Aspergillus fumigatus Af293
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4WF74 (Residues: 1-140; Coverage: 100%)
Gene name: AFUA_3G03220
Sequence domains: Putative oxalocrotonate tautomerase enzyme
Structure domains: Macrophage Migration Inhibitory Factor

Ligands and Environments

3 bound ligands:
Ligand NA 1 x NA
Ligand SO4 1 x SO4
Ligand CL 1 x CL
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 59.136Å b: 66.913Å c: 128.507Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 0.157 0.197
Expression system: Escherichia coli

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