› 3c8j

X-ray diffraction
2.6Å resolution

The crystal structure of natural killer cell receptor Ly49C

Released:
DOI: 10.2210/pdb3c8j/pdb
PDB entry 3c8j coloured by chain, front view.
PDB entry 3c8j coloured by chain, side view.
PDB entry 3c8j coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
Deng L, Cho S, Malchiodi EL, Kerzic MC, Dam J, Mariuzza RA
J Biol Chem 283 16840-9 (2008)
PMID: 18426793

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179115 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Killer cell lectin-like receptor 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 203 amino acids
Theoretical weight: 24.12 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q64329 (Residues: 64-123, 124-266; Coverage: 76%)
Gene names: Klra3, Ly-49c, Ly49C
Sequence domains:
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 69.097Å b: 94.892Å c: 104.192Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.198 0.263
Expression system: Escherichia coli BL21

Quick links

Citations

12 review citations

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation.
Wieczorek et al. (2017)
11 more

4 mentions without citation

Structural basis for recognition of cellular and viral ligands by NK cell receptors.
Li et al. (2014)
3 more