› 3c8w

X-ray diffraction
1.6Å resolution

Crystal structure of acetoacetate decarboxylase (ADC) (YP_094708.1) from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 at 1.60 A resolution

Released:
DOI: 10.2210/pdb3c8w/pdb
PDB entry 3c8w coloured by chain, front view.
PDB entry 3c8w coloured by chain, side view.
PDB entry 3c8w coloured by chain, top view.
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
Acetoacetate = acetone + CO(2)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178711 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetoacetate decarboxylase ADC Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 255 amino acids
Theoretical weight: 28.79 KDa
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5ZXQ9 (Residues: 1-254; Coverage: 100%)
Gene name: lpg0672
Sequence domains: Acetoacetate decarboxylase (ADC)
Structure domains: Acetoacetate decarboxylase-like

Ligands and Environments

1 bound ligand:
Ligand CIT 4 x CIT
2 modified residues:
Ligand MSE 24 x MSE
Ligand LCK 4 x LCK

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P63
Unit cell:
a: 104.1Å b: 104.1Å c: 189.64Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.193 0.228
Expression system: Escherichia coli

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