Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 240-mer (preferred)
Assembly name:
Capsid protein VP4 (preferred)
PDBe Complex ID:
PDB-CPX-172340 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Capsid protein VP1
Molecule details ›
Chain: A
Length: 263 amino acids
Theoretical weight: 29.09 KDa
Source organism: Senecavirus A
UniProt:
Length: 263 amino acids
Theoretical weight: 29.09 KDa
Source organism: Senecavirus A
UniProt:
- Canonical:
Q155Z9 (Residues: 674-936; Coverage: 12%)
Capsid protein VP3
Molecule details ›
Chain: B
Length: 239 amino acids
Theoretical weight: 26.49 KDa
Source organism: Senecavirus A
UniProt:
Structure domains: Jelly Rolls
Length: 239 amino acids
Theoretical weight: 26.49 KDa
Source organism: Senecavirus A
UniProt:
- Canonical: Q155Z9 (Residues: 435-673; Coverage: 11%)
Structure domains: Jelly Rolls
Capsid protein VP2
Molecule details ›
Chain: C
Length: 284 amino acids
Theoretical weight: 31.73 KDa
Source organism: Senecavirus A
UniProt:
Structure domains: Jelly Rolls
Length: 284 amino acids
Theoretical weight: 31.73 KDa
Source organism: Senecavirus A
UniProt:
- Canonical: Q155Z9 (Residues: 151-434; Coverage: 13%)
Structure domains: Jelly Rolls
Capsid protein VP4
Molecule details ›
Chain: D
Length: 71 amino acids
Theoretical weight: 7.39 KDa
Source organism: Senecavirus A
UniProt:
Length: 71 amino acids
Theoretical weight: 7.39 KDa
Source organism: Senecavirus A
UniProt:
- Canonical: Q155Z9 (Residues: 80-150; Coverage: 3%)
