Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190138 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polymerase acidic protein
Molecule details ›
Chain: A
Length: 471 amino acids
Theoretical weight: 53.87 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli
UniProt:
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA
Length: 471 amino acids
Theoretical weight: 53.87 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9EA60 (Residues: 256-716; Coverage: 64%)
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA
RNA-directed RNA polymerase catalytic subunit
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 3.19 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli
UniProt:
Length: 30 amino acids
Theoretical weight: 3.19 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli
UniProt:
- Canonical: Q9WLS3 (Residues: 1-25; Coverage: 3%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID, RIGAKU FR-E+ DW
Spacegroup:
P41212
Expression system: Escherichia coli
