› 3cmv

X-ray diffraction
4.3Å resolution

Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures

Released:
DOI: 10.2210/pdb3cmv/pdb
PDB entry 3cmv coloured by chain, front view.
PDB entry 3cmv coloured by chain, side view.
PDB entry 3cmv coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Chen Z, Yang H, Pavletich NP
Nature 453 489-4 (2008)
PMID: 18497818

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141594 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein RecA Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 1357 amino acids
Theoretical weight: 144.94 KDa
Source organism: Escherichia coli K-12
Expression system: Not provided
UniProt:
  • Canonical: P0A7G6 (Residues: 31-335, 2-335; Coverage: 95%)
Gene names: JW2669, b2699, lexB, recA, recH, rnmB, tif, umuB, zab
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand MG 32 x MG
Ligand ANP 32 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 176.6Å b: 189.8Å c: 424.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.243 0.261
Expression system: Not provided

Quick links

Citations

85 review citations

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis.
Moynahan et al. (2010)
84 more

8 mentions without citation

Targets for Combating the Evolution of Acquired Antibiotic Resistance.
Culyba et al. (2015)
7 more