› 3cnc

X-ray diffraction
2.4Å resolution

Crystal Structure of Ad16 fiber knob

Released:
DOI: 10.2210/pdb3cnc/pdb
PDB entry 3cnc coloured by chain, front view.
PDB entry 3cnc coloured by chain, side view.
PDB entry 3cnc coloured by chain, top view.
Source organism: Human adenovirus 16
Primary publication:
Structural variations in species B adenovirus fibers impact CD46 association.
Pache L, Venkataraman S, Reddy VS, Nemerow GR
J Virol 82 7923-31 (2008)
PMID: 18524830

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179300 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenoviral fibre protein knob domain-containing protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 220 amino acids
Theoretical weight: 24.11 KDa
Source organism: Human adenovirus 16
Expression system: Escherichia coli
UniProt:
  • Canonical: Q67711 (Residues: 151-353; Coverage: 58%)
Gene name: L5
Sequence domains: Adenoviral fibre protein (knob domain)
Structure domains: Adenovirus pIV-related, attachment domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P6522
Unit cell:
a: 167.83Å b: 167.83Å c: 262.161Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.245 0.245 0.272
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Adenovirus receptors: implications for tropism, treatment and targeting.
Arnberg N. (2009)
11 more

3 mentions without citation

Structural variations in species B adenovirus fibers impact CD46 association.
Pache et al. (2008)
2 more