› 3co2

X-ray diffraction
2.9Å resolution

Mlotik1 ion channel cyclic-nucleotide binding domain mutant

Released:
DOI: 10.2210/pdb3co2/pdb
PDB entry 3co2 coloured by chain, front view.
PDB entry 3co2 coloured by chain, side view.
PDB entry 3co2 coloured by chain, top view.
Source organism: Mesorhizobium loti
Primary publication:
Structural and energetic analysis of activation by a cyclic nucleotide binding domain.
Altieri SL, Clayton GM, Silverman WR, Olivares AO, De la Cruz EM, Thomas LR, Morais-Cabral JH
J Mol Biol 381 655-69 (2008)
PMID: 18619611

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189151 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclic nucleotide-gated potassium channel mll3241 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 140 amino acids
Theoretical weight: 14.87 KDa
Source organism: Mesorhizobium loti
Expression system: Escherichia coli
UniProt:
  • Canonical: Q98GN8 (Residues: 216-355; Coverage: 39%)
Gene name: mll3241
Sequence domains: Cyclic nucleotide-binding domain
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21212
Unit cell:
a: 111.473Å b: 132.349Å c: 39.822Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.263 0.261 0.306
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Cooperative and uncooperative cyclic-nucleotide-gated ion channels.
Cukkemane et al. (2011)
1 more

6 mentions without citation

Structural basis of properties, mechanisms, and channelopathy of cyclic nucleotide-gated channels.
Hu et al. (2023)
5 more