› 3co8

X-ray diffraction
1.7Å resolution

Crystal structure of alanine racemase from Oenococcus oeni

Released:
DOI: 10.2210/pdb3co8/pdb
PDB entry 3co8 coloured by chain, front view.
PDB entry 3co8 coloured by chain, side view.
PDB entry 3co8 coloured by chain, top view.
Source organism: Oenococcus oeni PSU-1
Primary publication:
Structure of alanine racemase from Oenococcus oeni with bound pyridoxal 5'-phosphate.
Palani K, Burley SK, Swaminathan S
Acta Crystallogr Sect F Struct Biol Cryst Commun 69 15-9 (2013)
PMID: 23295479

Function and Biology Details

Reaction catalysed: 
L-lysine = D-lysine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170101 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine racemase Chains: A, B
Molecule details ›
Chains: A, B
Length: 380 amino acids
Theoretical weight: 42.95 KDa
Source organism: Oenococcus oeni PSU-1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q04HB7 (Residues: 3-371; Coverage: 100%)
Gene name: OEOE_0162
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand PLP 2 x PLP
No bound ligands
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 47.397Å b: 99.639Å c: 84.67Å
α: 90° β: 103.26° γ: 90°
R-values:
R R work R free
0.247 0.247 0.259
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

Crystal Structure of a Thermostable Alanine Racemase from Thermoanaerobacter tengcongensis MB4 Reveals the Role of Gln360 in Substrate Selection.
Sun et al. (2015)

2 mentions without citation

The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design.
Im et al. (2011)
1 more