3cpf

X-ray diffraction
2.5Å resolution

Crystal structure of human eukaryotic translation initiation factor EIF5A

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-159060 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 5A-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 15.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P63241 (Residues: 15-151; Coverage: 89%)
Gene name: EIF5A
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P41212
Unit cell:
a: 76.119Å b: 76.119Å c: 107.752Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.246 0.244 0.3
Expression system: Escherichia coli