› 3ctg

X-ray diffraction
1.5Å resolution

Crystal structure of reduced glutaredoxin 2

Released:
DOI: 10.2210/pdb3ctg/pdb
PDB entry 3ctg coloured by chain, front view.
PDB entry 3ctg coloured by chain, side view.
PDB entry 3ctg coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural basis for the different activities of yeast Grx1 and Grx2.
Li WF, Yu J, Ma XX, Teng YB, Luo M, Tang YJ, Zhou CZ
Biochim Biophys Acta 1804 1542-7 (2010)
PMID: 20417731

Function and Biology Details

Reactions catalysed: 
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O
RX + glutathione = HX + R-S-glutathione
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148137 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutaredoxin-2 Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.15 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P17695 (Residues: 35-143; Coverage: 76%)
Gene names: D9719.17, GRX2, TTR, TTR1, YDR513W
Sequence domains: Glutaredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P43
Unit cell:
a: 41.63Å b: 41.63Å c: 78.39Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.199
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes.
Deponte M. (2013)
1 more

5 mentions without citation

Comparison of structures among Saccharomyces cerevisiae Grxs proteins.
Abdalla et al. (2018)
4 more