› 3d0s

X-ray diffraction
2Å resolution

cAMP receptor protein from m.tuberculosis, cAMP-free form

Released:
DOI: 10.2210/pdb3d0s/pdb
PDB entry 3d0s coloured by chain, front view.
PDB entry 3d0s coloured by chain, side view.
PDB entry 3d0s coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Entry authors: Gallagher DT, Robinson H, Reddy PT

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161793 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CRP-like cAMP-activated global transcriptional regulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 227 amino acids
Theoretical weight: 25.11 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WMH3 (Residues: 1-224; Coverage: 100%)
Gene names: Rv3676, crp
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 52.796Å b: 83.803Å c: 98.389Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.212 0.288
Expression system: Escherichia coli BL21(DE3)

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