› 3dgf

X-ray diffraction
2Å resolution

Structure of a histidine kinase-response regulator complex reveals insights into Two-component signaling and a novel cis-autophosphorylation mechanism

Released:
DOI: 10.2210/pdb3dgf/pdb
PDB entry 3dgf coloured by chain, front view.
PDB entry 3dgf coloured by chain, side view.
PDB entry 3dgf coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Structural insight into partner specificity and phosphoryl transfer in two-component signal transduction.
Casino P, Rubio V, Marina A
Cell 139 325-36 (2009)
PMID: 19800110

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194545 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Response regulatory domain-containing protein Chain: C
Molecule details ›
Chain: C
Length: 122 amino acids
Theoretical weight: 13.85 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WYT9 (Residues: 1-122; Coverage: 100%)
Gene name: TM_0468
Sequence domains: Response regulator receiver domain
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: P212121
Unit cell:
a: 34.574Å b: 55.476Å c: 58.428Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.211 0.259
Expression system: Escherichia coli

Quick links

Citations

46 review citations

Evolution of two-component signal transduction systems.
Capra et al. (2012)
45 more

10 mentions without citation

State-of-the-art anodes of potassium-ion batteries: synthesis, chemistry, and applications.
Li et al. (2021)
9 more