› 3dil

X-ray diffraction
1.9Å resolution

Crystal structure of the Thermotoga maritima lysine riboswitch bound to lysine

Released:
DOI: 10.2210/pdb3dil/pdb
PDB entry 3dil coloured by chain, front view.
PDB entry 3dil coloured by chain, side view.
PDB entry 3dil coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Structural insights into amino acid binding and gene control by a lysine riboswitch.
Serganov A, Huang L, Patel DJ
Nature 455 1263-7 (2008)
PMID: 18784651

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195853 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (174-MER) Chain: A
Molecule details ›
Chain: A
Length: 174 nucleotides
Theoretical weight: 56.64 KDa
Source organism: Thermotoga maritima
Expression system: Not provided
Sequence domains: Lysine riboswitch

Ligands and Environments

6 bound ligands:
Ligand LYS 1 x LYS
Ligand K 3 x K
Ligand NA 29 x NA
Ligand MG 1 x MG
Ligand 1PE 3 x 1PE
Ligand IPA 1 x IPA
1 modified residue:
Ligand CCC 1 x CCC

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P212121
Unit cell:
a: 54.216Å b: 78.953Å c: 139.988Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.229
Expression system: Not provided

Quick links

Citations

41 review citations

A decade of riboswitches.
Serganov et al. (2013)
40 more

24 mentions without citation

The structural and functional diversity of metabolite-binding riboswitches.
Roth et al. (2009)
23 more