› 3dmo

X-ray diffraction
1.6Å resolution

1.6 A crystal structure of cytidine deaminase from Burkholderia pseudomallei

Released:
DOI: 10.2210/pdb3dmo/pdb
PDB entry 3dmo coloured by chain, front view.
PDB entry 3dmo coloured by chain, side view.
PDB entry 3dmo coloured by chain, top view.
Source organism: Burkholderia pseudomallei
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
2'-deoxycytidine + H(2)O = 2'-deoxyuridine + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174633 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytidine deaminase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 138 amino acids
Theoretical weight: 14.67 KDa
Source organism: Burkholderia pseudomallei
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q3JJN0 (Residues: 1-130; Coverage: 100%)
Gene names: BURPS1710b_A1065, cdd
Sequence domains: Cytidine and deoxycytidylate deaminase zinc-binding region
Structure domains: Cytidine Deaminase, domain 2

Ligands and Environments

3 bound ligands:
Ligand ZN 4 x ZN
Ligand MRD 4 x MRD
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P21
Unit cell:
a: 60.495Å b: 72.308Å c: 83.327Å
α: 90° β: 111.29° γ: 90°
R-values:
R R work R free
0.2 0.199 0.224
Expression system: Escherichia coli BL21(DE3)

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