› 3drz

X-ray diffraction
1.9Å resolution

X-ray crystal structure of the N-terminal BTB domain of human KCTD5 protein

Released:
DOI: 10.2210/pdb3drz/pdb
PDB entry 3drz coloured by chain, front view.
PDB entry 3drz coloured by chain, side view.
PDB entry 3drz coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Pentameric assembly of potassium channel tetramerization domain-containing protein 5.
Dementieva IS, Tereshko V, McCrossan ZA, Solomaha E, Araki D, Xu C, Grigorieff N, Goldstein SA
J Mol Biol 387 175-91 (2009)
PMID: 19361449

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192688 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BTB/POZ domain-containing protein KCTD5 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 107 amino acids
Theoretical weight: 12.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NXV2 (Residues: 40-145; Coverage: 45%)
Gene name: KCTD5
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 59.039Å b: 90.718Å c: 110.158Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.194 0.232
Expression system: Escherichia coli

Quick links

Citations

4 review citations

KCTD: A new gene family involved in neurodevelopmental and neuropsychiatric disorders.
Teng et al. (2019)
3 more

6 mentions without citation

Pentameric assembly of potassium channel tetramerization domain-containing protein 5.
Dementieva et al. (2009)
5 more