› 3dwo

X-ray diffraction
2.2Å resolution

Crystal structure of a Pseudomonas aeruginosa FadL homologue

Released:
DOI: 10.2210/pdb3dwo/pdb
PDB entry 3dwo coloured by chain, front view.
PDB entry 3dwo coloured by chain, side view.
PDB entry 3dwo coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Transmembrane passage of hydrophobic compounds through a protein channel wall.
Hearn EM, Patel DR, Lepore BW, Indic M, van den Berg B
Nature 458 367-70 (2009)
PMID: 19182779

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191015 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable outer membrane protein Chain: X
Molecule details ›
Chain: X
Length: 451 amino acids
Theoretical weight: 48.91 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HVJ6 (Residues: 22-463; Coverage: 100%)
Gene name: PA4589
Sequence domains: Outer membrane protein transport protein (OMPP1/FadL/TodX)
Structure domains: Outer membrane protein transport protein (OMPP1/FadL/TodX)

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand C8E 11 x C8E
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2221
Unit cell:
a: 56.777Å b: 233.054Å c: 81.899Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.213 0.253
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation.
Kamaly et al. (2012)
14 more

13 mentions without citation

The structural biology of β-barrel membrane proteins: a summary of recent reports.
Fairman et al. (2011)
12 more