Function and Biology Details
Reaction catalysed:
Man(5)GlcNAc(3)-[protein] + 2 H(2)O = Man(3)GlcNAc(3)-[protein] + 2 alpha-D-mannopyranose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Glycoside hydrolase family 38, central domain
- Alpha-mannosidase 2, C-terminal sub-domain
- Glycosyl hydrolase family 38, C-terminal
- Glycosyl hydrolase, all-beta
- Galactose mutarotase-like domain superfamily
- Glycoside hydrolase families 57/38, central domain superfamily
- Glycoside hydrolase family 38, central domain superfamily
- Glycoside hydrolase family 38, N-terminal domain
2 more domains
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Alpha-mannosidase 2 (preferred)
PDBe Complex ID:
PDB-CPX-173193 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-mannosidase 2
Molecule details ›
Chain: A
Length: 1045 amino acids
Theoretical weight: 119.7 KDa
Source organism: Drosophila melanogaster
Expression system: Drosophila melanogaster
UniProt:
Sequence domains:
Length: 1045 amino acids
Theoretical weight: 119.7 KDa
Source organism: Drosophila melanogaster
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
Q24451 (Residues: 76-1108; Coverage: 93%)
Sequence domains:
- Glycosyl hydrolases family 38 N-terminal domain
- Alpha mannosidase middle domain
- Lysosomal alpha-mannosidase-like, central domain
- Glycosyl hydrolases family 38 C-terminal domain
- Glycosyl hydrolases family 38 C-terminal sub-domain
