Function and Biology Details
Reaction catalysed:
L-tryptophan + tetrahydrobiopterin + O(2) = 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assemblies composition:
Assembly name:
Tryptophan 5-hydroxylase 1 (preferred)
PDBe Complex ID:
PDB-CPX-159704 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tryptophan 5-hydroxylase 1
Molecule details ›
Chain: A
Length: 314 amino acids
Theoretical weight: 36.14 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
Sequence domains: Biopterin-dependent aromatic amino acid hydroxylase
Structure domains: Aromatic amino acid hydroxylase
Length: 314 amino acids
Theoretical weight: 36.14 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
- Canonical:
P70080 (Residues: 101-414; Coverage: 71%)
Sequence domains: Biopterin-dependent aromatic amino acid hydroxylase
Structure domains: Aromatic amino acid hydroxylase
