› 3e3a

X-ray diffraction
2.35Å resolution

The Structure of Rv0554 from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb3e3a/pdb
PDB entry 3e3a coloured by chain, front view.
PDB entry 3e3a coloured by chain, side view.
PDB entry 3e3a coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis.
Johnston JM, Jiang M, Guo Z, Baker EN
Acta Crystallogr D Biol Crystallogr 66 909-17 (2010)
PMID: 20693690

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161858 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative non-heme bromoperoxidase BpoC Chains: A, B
Molecule details ›
Chains: A, B
Length: 293 amino acids
Theoretical weight: 32.25 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WNH1 (Residues: 2-262; Coverage: 100%)
Gene names: Rv0554, bpoC
Sequence domains: alpha/beta hydrolase fold
Structure domains: alpha/beta hydrolase

Ligands and Environments

2 bound ligands:
Ligand ACT 2 x ACT
Ligand MPD 1 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P212121
Unit cell:
a: 48.704Å b: 97.89Å c: 146.165Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.173 0.238
Expression system: Escherichia coli

Quick links

Citations

7 citation in other articles

Systematic Survey of Serine Hydrolase Activity in Mycobacterium tuberculosis Defines Changes Associated with Persistence.
Ortega et al. (2016)
6 more