› 3ead

X-ray diffraction
2.25Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-221520 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calx-beta domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 137 amino acids
Theoretical weight: 15.48 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0B4K6E2 (Residues: 438-574; Coverage: 14%)
Gene names: 9C5, CALX, CALX1.1, CG5685, CalX, Calx, Dmel/Ncx, Dmel\CG5685, Dmel_CG5685, NCX, Ncx, anon-93ABa, calX, calx
Sequence domains: Calx-beta domain
Structure domains: Immunoglobulin-like

Ligands and Environments

2 bound ligands:
Ligand CA 16 x CA
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 59.372Å b: 73.722Å c: 129.713Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.21 0.269
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Na+/Ca2+ exchange and Na+/K+-ATPase in the heart.
Shattock et al. (2015)
8 more

1 mention without citation

Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions.
Wu et al. (2010)