› 3ec8

X-ray diffraction
2.6Å resolution

The crystal structure of the RA domain of FLJ10324 (RADIL)

Released:
DOI: 10.2210/pdb3ec8/pdb
PDB entry 3ec8 coloured by chain, front view.
PDB entry 3ec8 coloured by chain, side view.
PDB entry 3ec8 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wisniewska M, Lehtio L, Andersson J, Arrowsmith CH, Collins R, Dahlgren LG, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson A, Johansson I, Karlberg T, Kotenyova T, Moche M, Nilsson ME, Nordlund P, Nyman T, Olesen K, Persson C, Sagemark J, Schueler H, Thorsell AG, Tresaugues L, van den Berg S, Weigelt J, Welin M, Wikstrom M, Berglund H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-188574 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-associating and dilute domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 166 amino acids
Theoretical weight: 18.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96JH8 (Residues: 51-193; Coverage: 13%)
Gene names: KIAA1849, RADIL
Sequence domains: Ras association (RalGDS/AF-6) domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

3 bound ligands:
Ligand CL 1 x CL
Ligand PB 2 x PB
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P3112
Unit cell:
a: 46.08Å b: 46.08Å c: 135.61Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.227 0.27
Expression system: Escherichia coli

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