3eco

X-ray diffraction
2.4Å resolution

Crystal structure of MepR, a transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-101933 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH marR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 139 amino acids
Theoretical weight: 16.19 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3JPT9 (Residues: 1-139; Coverage: 100%)
Gene name: SAV0333
Sequence domains: MarR family
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 32.196Å b: 96.574Å c: 110.283Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.242 0.242 0.289
Expression system: Escherichia coli