› 3egn

X-ray diffraction
2.5Å resolution

C-terminal RNA Recognition Motif of the U11/U12 65K Protein

Released:
DOI: 10.2210/pdb3egn/pdb
PDB entry 3egn coloured by chain, front view.
PDB entry 3egn coloured by chain, side view.
PDB entry 3egn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Functional stabilization of an RNA recognition motif by a noncanonical N-terminal expansion.
Netter C, Weber G, Benecke H, Wahl MC
RNA 15 1305-13 (2009)
PMID: 19447915

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188624 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-binding region-containing protein 3 Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96LT9 (Residues: 380-517; Coverage: 27%)
Gene names: KIAA1839, RBM40, RNP, RNPC3, SNRNP65
Sequence domains: RNA recognition motif
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 90.973Å b: 33.499Å c: 49.312Å
α: 90° β: 96.64° γ: 90°
R-values:
R R work R free
0.199 0.194 0.236
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structural insight into RNA recognition motifs: versatile molecular Lego building blocks for biological systems.
Muto et al. (2012)
10 other articles

5 mentions without citation

Defective minor spliceosome mRNA processing results in isolated familial growth hormone deficiency.
Argente et al. (2014)
4 more