› 3ego

X-ray diffraction
1.9Å resolution

Crystal structure of Probable 2-dehydropantoate 2-reductase panE from Bacillus Subtilis

Released:
DOI: 10.2210/pdb3ego/pdb
PDB entry 3ego coloured by chain, front view.
PDB entry 3ego coloured by chain, side view.
PDB entry 3ego coloured by chain, top view.
Source organism: Bacillus subtilis
Entry authors: Ramagopal UA, Toro R, Gilmore M, Hu S, Maletic M, Gheyi T, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128574 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-dehydropantoate 2-reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 307 amino acids
Theoretical weight: 34.4 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O34661 (Residues: 2-297; Coverage: 99%)
Gene names: BSU15110, apbA, panE, ylbQ
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2
Unit cell:
a: 160.86Å b: 43.658Å c: 83.757Å
α: 90° β: 98.26° γ: 90°
R-values:
R R work R free
0.207 0.204 0.26
Expression system: Escherichia coli BL21(DE3)

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