3ehs

X-ray diffraction
2.76Å resolution

Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-142532 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Corticotropin-releasing factor receptor 1; Maltose/maltodextrin-binding periplasmic protein Chain: A
Molecule details ›
Chain: A
Length: 476 amino acids
Theoretical weight: 52.55 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P0AEX9 (Residues: 25-392; Coverage: 99%)
  • Canonical: P34998 (Residues: 24-119; Coverage: 23%)
Gene names: CRFR, CRFR1, CRHR, CRHR1, JW3994, b4034, malE
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P41212
Unit cell:
a: 112.018Å b: 112.018Å c: 145.786Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.207 0.24
Expression system: Escherichia coli