› 3emu

X-ray diffraction
2.3Å resolution

Crystal structure of a leucine rich repeat and phosphatase domain containing protein from Entamoeba histolytica

Released:
DOI: 10.2210/pdb3emu/pdb
PDB entry 3emu coloured by chain, front view.
PDB entry 3emu coloured by chain, side view.
PDB entry 3emu coloured by chain, top view.
Source organism: Entamoeba histolytica HM-1:IMSS
Entry authors: Bonanno JB, Gilmore M, Bain KT, Hu S, Ozyurt S, Wasserman S, Sauder JM, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112185 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 161 amino acids
Theoretical weight: 18.37 KDa
Source organism: Entamoeba histolytica HM-1:IMSS
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D0VX03 (Residues: 1-161; Coverage: 100%)
Gene name: EHI_044170
Sequence domains: Dual specificity phosphatase, catalytic domain
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P3121
Unit cell:
a: 80.985Å b: 80.985Å c: 90.556Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.23 0.236
Expression system: Escherichia coli BL21(DE3)

Quick links