› 3eop

X-ray diffraction
2.3Å resolution

Crystal Structure of the DUF55 domain of human thymocyte nuclear protein 1

Released:
DOI: 10.2210/pdb3eop/pdb
PDB entry 3eop coloured by chain, front view.
PDB entry 3eop coloured by chain, side view.
PDB entry 3eop coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Determining the DUF55-domain structure of human thymocyte nuclear protein 1 from crystals partially twinned by tetartohedry.
Yu F, Song A, Xu C, Sun L, Li J, Tang L, Yu M, Yeates TO, Hu H, He J
Acta Crystallogr D Biol Crystallogr 65 212-9 (2009)
PMID: 19237743

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192795 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thymocyte nuclear protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 176 amino acids
Theoretical weight: 20.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9P016 (Residues: 55-221; Coverage: 74%)
Gene names: HSPC144, MDS012, My0054, THY28, THYN1
Sequence domains: EVE domain
Structure domains: ph1033 like domains

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P31
Unit cell:
a: 51.258Å b: 51.258Å c: 122.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.182 0.238
Expression system: Escherichia coli

Quick links

Citations

5 citation in other articles

Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain.
Luo et al. (2014)
4 more

4 mentions without citation

Tetartohedral twinning could happen to you too.
Roversi et al. (2012)
3 more