› 3ep0

X-ray diffraction
2.1Å resolution

Methyltransferase domain of human PR domain-containing protein 12

Released:
DOI: 10.2210/pdb3ep0/pdb
PDB entry 3ep0 coloured by chain, front view.
PDB entry 3ep0 coloured by chain, side view.
PDB entry 3ep0 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Amaya MF, Zeng H, Loppnau P, Bountra C, Weigelt J, Arrowsmith CH, Edwards AM, Botchkarev A, Min J, Plotnikov AN, Wu H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190617 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PR domain zinc finger protein 12 Chains: A, B
Molecule details ›
Chains: A, B
Length: 170 amino acids
Theoretical weight: 19.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H4Q4 (Residues: 60-229; Coverage: 46%)
Gene names: PFM9, PRDM12
Sequence domains: SET domain
Structure domains: SET domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: C2
Unit cell:
a: 138.882Å b: 34.358Å c: 103.739Å
α: 90° β: 131.09° γ: 90°
R-values:
R R work R free
0.259 0.257 0.286
Expression system: Escherichia coli

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