› 3etf

X-ray diffraction
1.85Å resolution

Crystal structure of a putative succinate-semialdehyde dehydrogenase from salmonella typhimurium lt2

Released:
DOI: 10.2210/pdb3etf/pdb
PDB entry 3etf coloured by chain, front view.
PDB entry 3etf coloured by chain, side view.
PDB entry 3etf coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Primary publication:
Structure and activity of the NAD(P)+-dependent succinate semialdehyde dehydrogenase YneI from Salmonella typhimurium.
Zheng H, Beliavsky A, Tchigvintsev A, Brunzelle JS, Brown G, Flick R, Evdokimova E, Wawrzak Z, Mahadevan R, Anderson WF, Savchenko A, Yakunin AF
Proteins 81 1031-41 (2013)
PMID: 23229889

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187334 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldehyde dehydrogenase domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 462 amino acids
Theoretical weight: 49.72 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8ZPI3 (Residues: 1-462; Coverage: 100%)
Gene names: STM1524, yneI
Sequence domains: Aldehyde dehydrogenase family
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 60 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P3221
Unit cell:
a: 133.875Å b: 133.875Å c: 247.028Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.194
Expression system: Escherichia coli

Quick links

Citations

11 citation in other articles

Structure-based mutational studies of substrate inhibition of betaine aldehyde dehydrogenase BetB from Staphylococcus aureus.
Chen et al. (2014)
10 more

1 mention without citation

Homotaurine metabolized to 3-sulfopropanoate in Cupriavidus necator H16: enzymes and genes in a patchwork pathway.
Mayer et al. (2009)