› 3etp

X-ray diffraction
2Å resolution

The crystal structure of the ligand-binding domain of the EphB2 receptor at 2.0 A resolution

Released:
DOI: 10.2210/pdb3etp/pdb
PDB entry 3etp coloured by chain, front view.
PDB entry 3etp coloured by chain, side view.
PDB entry 3etp coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution.
Goldgur Y, Paavilainen S, Nikolov D, Himanen JP
Acta Crystallogr Sect F Struct Biol Cryst Commun 65 71-4 (2009)
PMID: 19193989

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157093 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ephrin type-B receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 187 amino acids
Theoretical weight: 21.44 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P54763 (Residues: 20-199; Coverage: 19%)
Gene names: Ephb2, Epth3, Nuk, Sek3
Sequence domains: Ephrin receptor ligand binding domain
Structure domains: Galactose-binding domain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P41212
Unit cell:
a: 54.028Å b: 54.028Å c: 157.412Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.198 0.263
Expression system: Escherichia coli

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Citations

4 citation in other articles

Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Himanen et al. (2009)
3 more

4 mentions without citation

Harnessing protein folding neural networks for peptide-protein docking.
Tsaban et al. (2022)
3 more