› 3etu

X-ray diffraction
2.4Å resolution

Crystal structure of yeast Dsl1p

Released:
DOI: 10.2210/pdb3etu/pdb
PDB entry 3etu coloured by chain, front view.
PDB entry 3etu coloured by chain, side view.
PDB entry 3etu coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.
Tripathi A, Ren Y, Jeffrey PD, Hughson FM
Nat Struct Mol Biol 16 114-23 (2009)
PMID: 19151722

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156886 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein transport protein DSL1 Chain: A
Molecule details ›
Chain: A
Length: 365 amino acids
Theoretical weight: 42.02 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P53847 (Residues: 1-361; Coverage: 48%)
Gene names: DSL1, N0842, YNL258C
Sequence domains: Retrograde transport protein Dsl1 N terminal
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P3221
Unit cell:
a: 110.62Å b: 110.62Å c: 77.203Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.229 0.266
Expression system: Escherichia coli

Quick links

Citations

30 review citations

Role of Rab GTPases in membrane traffic and cell physiology.
Hutagalung et al. (2011)
29 more

6 mentions without citation

A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1.
Ren et al. (2009)
5 more