› 3etx

X-ray diffraction
3Å resolution

Crystal structure of bacterial adhesin FadA L14A mutant

Released:
DOI: 10.2210/pdb3etx/pdb
Model geometry
Fit model/data
PDB entry 3etx coloured by chain, front view.
PDB entry 3etx coloured by chain, side view.
PDB entry 3etx coloured by chain, top view.
Source organism: Fusobacterium nucleatum
Primary publication:
Crystal structure of FadA adhesin from Fusobacterium nucleatum reveals a novel oligomerization motif, the leucine chain.
Nithianantham S, Xu M, Yamada M, Ikegami A, Shoham M, Han YW
J Biol Chem 284 3865-72 (2009)
PMID: 18996848

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adhesion A Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 119 amino acids
Theoretical weight: 13.63 KDa
Source organism: Fusobacterium nucleatum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5I6B0 (Residues: 19-129; Coverage: 100%)
Gene names: DNF10_04660, fadA
Sequence domains: Adhesion protein FadA
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P21
Unit cell:
a: 59.317Å b: 104.805Å c: 59.854Å
α: 90° β: 105.1° γ: 90°
R-values:
R R work R free
0.298 0.238 0.28
Expression system: Escherichia coli

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Citations

11 review citations

Mobile microbiome: oral bacteria in extra-oral infections and inflammation.
Han et al. (2013)
10 more

2 mentions without citation

The structures of coiled-coil domains from type III secretion system translocators reveal homology to pore-forming toxins.
Barta et al. (2012)
1 more