› 3exv

X-ray diffraction
1.45Å resolution

Crystal structure of the human Adenovirus type 11 fiber knob

Released:
DOI: 10.2210/pdb3exv/pdb
PDB entry 3exv coloured by chain, front view.
PDB entry 3exv coloured by chain, side view.
PDB entry 3exv coloured by chain, top view.
Source organism: Human mastadenovirus B
Primary publication:
An arginine switch in the species B adenovirus knob determines high-affinity engagement of cellular receptor CD46.
Persson BD, Müller S, Reiter DM, Schmitt BB, Marttila M, Sumowski CV, Schweizer S, Scheu U, Ochsenfeld C, Arnberg N, Stehle T
J Virol 83 673-86 (2009)
PMID: 18987134

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153019 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fiber protein Chain: A
Molecule details ›
Chain: A
Length: 213 amino acids
Theoretical weight: 23.75 KDa
Source organism: Human mastadenovirus B
Expression system: Escherichia coli
UniProt:
  • Canonical: P35774 (Residues: 117-325; Coverage: 64%)
Gene name: L5
Sequence domains: Adenoviral fibre protein (knob domain)
Structure domains: Adenovirus pIV-related, attachment domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: I23
Unit cell:
a: 100.597Å b: 100.597Å c: 100.597Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.225
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Latest insights on adenovirus structure and assembly.
San Martín C. (2012)
7 more

4 mentions without citation

An arginine switch in the species B adenovirus knob determines high-affinity engagement of cellular receptor CD46.
Persson et al. (2009)
3 more