3eyq

X-ray diffraction
2.4Å resolution

Crystal structure of MJ5 Fab, a germline antibody variant of anti-human cytomegalovirus antibody 8f9

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-171205 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chain: C
Molecule details ›
Chain: C
Length: 216 amino acids
Theoretical weight: 23.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PIL8 (Residues: 21-236; Coverage: 100%)
Gene name: IGK@
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chain: D
Molecule details ›
Chain: D
Length: 242 amino acids
Theoretical weight: 25.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0ZCI9 (Residues: 1-126; Coverage: 99%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 65.38Å b: 76.05Å c: 111.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.25 0.27
Expression system: Escherichia coli